Friday, March 20, 2009

Accelerating evolution

Multiplex-automated genomic engineering, or MAGE, is a revolutionary technique in genome sequencing pioneered by George Church, PhD at Harvard, MIT, Boston University, and University of Cambridge. Rather than step-by-step alterations to a genetic code, MAGE enacts numerous changes throughout the genome simultaneously. The experiments on bacteria thus far have accelerated genome sequencing exponentially, condensing work that would take months into a turnaround of a few days. This innovation holds promise to genetically modify bacteria instrumental in pharmaceuticals and biofuels to be more productive. MIT's Technology Review offers more details.

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